Have tried many probiotics. My gastroenterologist recommended I take a good probiotic for my G.I. issues. Don’t waste your money on grocery store products. This is the best one I have found.I've used it to help with my acid reflux amd other digestive issues for years and I also used it to combat the severe side effects of antibiotics. It works. It really works!!!!Many cultures, best one I've found on the market. Nix hormonal belly in a months time. Perfect size & Comes in a great thick reuseable bottle as all probiotics should..Original product and quality would purchase again.3 things were different than past orders of this probiotic: 1. It did not come in a box. 2. Has a bad oder and taste and 3. Had two labels on it which just seems weird.I have purchased this more than one in the past and thought it was fantastic. I’ll be returning this bottle and reorder. Hopefully this one is a fluke.UPDATE 4/04/21: Ordered another bottle of this and it too smells and tastes like plastic and does nothing. Kinda made me afraid of what I was ingesting. Sorry Nature’s Plus, this one’s off my list.This is my go to probiotic for my son when he's having a flare from PANDAS. Within a couple of days he's calmer and happier.Could not tell a difference if I used or didn’t. Looking for less expensive product but this for me was a fail.I took as directed, nothing, I took larger amounts, nothing. I love Natures Plus and recommend their products to anyone that will listen, But this for me was a do nothing product. Maybe it was old, or heat exposed, or.....? Not the quality or effectiveness I expect from Natures Plus!